Super-Paramagnetic Iron Oxide Tracer

For Pre-clinical Magnetic Resonance and Magnetic Particle Imaging

VivoTrax is for use in research MRI and MPI to track cells non-invasively in vivo or vacular imaging. It is a simple to use nanoparticle for loading into cells for cell tracking experiments and as a blood pool agent. The dextran magnetite solution is well characterized and has been widely used with magnetic resonance and magnetic particle imaging.

VivoTrax is one of the few available tracers proven on magnetic particle imaging due to their unique magnetic properties. Certain dextran magnetites are not only used for cell tracking, but approved for clinical imaging in many countries to detect liver carcinomas.

VivoTrax is available in 5-tube and 10-tube packages. Each vial contains 1.1 mL of VivoTrax superparamagnetic iron oxide (SPIO) dextran magnetite nanoparticle solution, comprising ~5.5 mg/mL total iron and ~6 mg/mL carboxydextran in sterilized PBS Endotoxins <0.5 EU/mg Fe.

Left: Vivotrax, Right: Prussian blue staining of mesenchymal stem cells labeled with VivoTrax, Bottom: Tracking I.V. injected mesenchymal stem cells.