Journal Publications

  • Tomographic magnetic particle imaging of cancer targeted nanoparticles
    Hamed Arami, Eric Teeman, Alyssa Troksa, Haydin Bradshaw, Katayoun Saatchi, Asahi Tomitaka, Sanjiv Sam Gambhir, Urs O. Häfeli, Denny Liggittg and Kannan M. Krishnan Nanoscale, 2017,9, 18723-18730 DOI:10.1039/C7NR05502A
  • Hybrid magneto-plasmonic liposomes for multimodal image-guided and brain-targeted HIV treatment. Asahi Tomitaka, Hamed Arami, Zaohua Huang, Andrea Raymond, Elizette Rodriguez, Yong Cai, Marcelo Febo, Yasushi Takemura and Madhavan Nair. Nanoscale, 2017, Advance Article DOI: 10.1039/C7NR07255D
  • Magnetic Particle Imaging for Highly Sensitive, Quantitative, and Safe in Vivo Gut Bleed Detection in a Murine Model. Elaine Y. Yu, Prashant Chandrasekharan, Ran Berzon, Zhi Wei Tay, Xinyi Y. Zhou, Amit P. Khandhar, R. Matthew Ferguson, Scott J. Kemp, Bo Zheng, Patrick W. Goodwill, Michael F. Wendland, Kannan M. Krishnan, Spencer Behr, Jonathan Carter, and Steven M. Conolly. ACS Nano DOI: 10.1021/acsnano.7b04844
  • First in vivo magnetic particle imaging of lung perfusion in rats. Zhou XY, Jeffris K, Yu E, Zheng B, Goodwill P, Nahid P, Conolly S. Phys Med Biol. 2017 Feb 20. doi: 10.1088/1361-6560/aa616c. [Epub ahead of print]
  • Magnetic Particle Imaging: A Novel in Vivo Imaging Platform for Cancer Detection. Yu EY, Bishop M, Zheng B, Ferguson RM, Khandhar AP, Kemp SJ, Krishnan KM, Goodwill PW, Conolly SM. Nano Lett. 2017 Feb 21. doi: 10.1021/acs.nanolett.6b04865. [Epub ahead of print]
  • Tracking short-term biodistribution and long-term clearance of SPIO tracers in magnetic particle imaging. Keselman P, Yu E, Zhou X, Goodwill P, Chandrasekharan P, Ferguson RM, Khandhar A, Kemp S, Krishnan K, Zheng B, Conolly S. Phys Med Biol. 2017 Feb 8. doi: 10.1088/1361-6560/aa5f48. [Epub ahead of print]
  • Evaluation of PEG-coated iron oxide nanoparticles as blood pool tracers for preclinical magnetic particle imaging. Khandhar AP, Keselman P, Kemp SJ, Ferguson RM, Goodwill PW, Conolly SM, Krishnan KM. Nanoscale. 2017 Jan 19;9(3):1299-1306. doi: 10.1039/c6nr08468k.
  • Combining magnetic particle imaging and magnetic fluid hyperthermia in a theranostic platform. Hensley DW, Tay ZW, Dhavalikar R, Zheng B, Goodwill P, Rinaldi C, Conolly S. Phys Med Biol. 2016 Dec 29. doi: 10.1088/1361-6560/aa5601. [Epub ahead of print]
  • Finite magnetic relaxation in x-space magnetic particle imaging: Comparison of measurements and ferrohydrodynamic models. Dhavalikar R, Hensley D, Maldonado-Camargo L, Croft LR, Ceron S, Goodwill PW, Conolly SM, Rinaldi C. J Phys D Appl Phys. 2016 Aug 3;49(30). pii: 305002.
  • A High-Throughput, Arbitrary-Waveform, MPI Spectrometer and Relaxometer for Comprehensive Magnetic Particle Optimization and Characterization. Tay ZW, Goodwill PW, Hensley DW, Taylor LA, Zheng B, Conolly SM. Sci Rep. 2016 Sep 30;6:34180. doi: 10.1038/srep34180.
  • Eddy current-shielded x-space relaxometer for sensitive magnetic nanoparticle characterization. Bauer LM, Hensley DW, Zheng B, Tay ZW, Goodwill PW, Griswold MA, Conolly SM. Rev Sci Instrum. 2016 May;87(5):055109. doi: 10.1063/1.4950779.
  • Quantitative Magnetic Particle Imaging Monitors the Transplantation, Biodistribution, and Clearance of Stem Cells In Vivo. Zheng B, von See MP, Yu E, Gunel B, Lu K, Vazin T, Schaffer DV, Goodwill PW, Conolly SM. Theranostics. 2016 Jan 1;6(3):291-301. doi: 10.7150/thno.13728. Free PMC Article
  • Low drive field amplitude for improved image resolution in magnetic particle imaging. Croft LR, Goodwill PW, Konkle JJ, Arami H, Price DA, Li AX, Saritas EU, Conolly SM. Med Phys. 2016 Jan;43(1):424. doi: 10.1118/1.4938097.
  • Quantitative Magnetic Particle Imaging Monitors the Transplantation, Biodistribution, and Clearance of Stem Cells In Vivo. B Zheng et al., Theranostics, 2016; 6(3): 291-301.
  • Low drive field amplitude for improved image resolution in magnetic particle imaging. LR Croft et al, Medical Physics, 43.1 (2016): 424-435.
  • Magnetic nanoparticles: material engineering and emerging applications in lithography and biomedicine. Y Bao et al., Journal of Materials Science, 51.1 (2016): 513-553.
  • A Convex Formulation for Magnetic Particle Imaging X-Space Reconstruction. JJ Konkle, PW Goodwill, DW Hensley, RD Orendorff, M Lustig, SM Conolly, PLoS One, 2015 Oct 23;10(10):e0140137. doi: 10.1371/journal.pone.0140137. eCollection 2015.PMID: 26495839. Free Article.
  • Lactoferrin conjugated iron oxide nanoparticles for targeting brain glioma cells in magnetic particle imaging. A Tomitaka, H Arami, S Gandhi, KM Krishnan, Nanoscale, 2015 Oct 8;7(40):16890-8. doi: 10.1039/c5nr02831k. PMID: 2641261.
  • Magnetic Particle Imaging tracks the long-term fate of in vivo neural cell implants with high image contrast. B Zheng, T Vazin, PW Goodwill, A Conway, A Verma, E Ulku Saritas, D Schaffer, SM Conolly, Sci Rep, 2015 Sep 11; 5:14055. doi: 10.1038/srep14055.PMID: 26358296. Free PMC Article.
  • Magnetic Particle Imaging Tracers: State-of-the-Art and Future Directions. LM Bauer, SF Situ, MA Griswold, AC Samia, J Phys Chem Lett, 2015 Jul 2;6(13):2509-17. doi: 10.1021/acs.jpclett.5b00610. Epub 2015 Jun 17. PMID: 26266727.
  • Effects of pulse duration on magnetostimulation thresholds. EU Saritas, PW Goodwill, SM Conolly, Med Phys, 2015 Jun;42(6):3005-12. doi:10.1118/1.4921209. PMID: 26127053
  • Usefulness of Magnetic Particle Imaging for Predicting the Therapeutic Effect of Magnetic Hyperthermia. K Murase, M Aoki, N Banura, K Nishimoto, A Mimura, T Kuboyabu, I Yabata, Open Journal of Medical Imaging, 2015. Free Article.
  • Linearity and Shift-Invariance For Quantitative Magnetic Particle Imaging. K Lu, PW Goodwill, EU Saritas, B Zheng, SM Conolly, IEEE Transactions on Medical Img, 32(9), 2013.
  • Projection Reconstruction Magnetic Particle Imaging. JJ Konkle, PW Goodwill, O Carrasco-Zevallos, SM Conolly, IEEE Trans Med Img, 32(2), 2013.
  • Magnetic Particle Imaging (MPI) for NMR and MRI Researchers. EU Saritas, PW Goodwill, LR Croft, JJ Konkle, K Lu, B Zheng, SM Conolly, Journal of Magnetic Resonance, 229, 2013.
  • Magnetostimulation Limits in Magnetic Particle Imaging. EU Saritas, PW Goodwill, GZ Zhang, SM Conolly, IEEE Trans Med Img, 32(9), 2013.
  • Twenty-fold acceleration of 3D projection reconstruction MPI. JJ Konkle, PW Goodwill, EU Saritas, B Zheng, K Lu, SM Conolly, Biomedizinische Technik/Biomedical Engineering, 58(6), 565-76, 2013.
  • X-space MPI: Magnetic Nanoparticles for Safe Medical Imaging. W Goodwill, EU Saritas, LR Croft, TN Kim, KM Krishnan, DV Schaffer, SM Conolly, Advanced Materials, 24 (28), 3870-3877, 2012.
  • Projection X-Space Magnetic Particle Imaging. PW Goodwill, J Konkle, B Zheng, S Conolly, IEEE Trans Med Img, 31(5), 1076-85, 2012.
  • An X-Space Magnetic Particle Imaging Scanner. PW Goodwill, K Lu, B Zheng, S Conolly, Review of Scientific Instruments, 83, 033708, 2012.
  • Relaxation in X-Space Magnetic Particle Imaging. L Croft, PW Goodwill, SM Conolly, IEEE Trans Med Img, 31(12), 2012.
  • Multidimensional X-space Magnetic Particle Imaging. PW Goodwill, SM Conolly, IEEE Trans Med Img, 30(9), 2011.
  • First phantom and in vivo MPI images with an extended field of view. I Schmale, J Rahmer, B Gleich, J Kanzenbach, JD Schmidt, C Bontus, O Woywode, J Borgert, Proceedings of SPIE, 7965, 796510—796510-6, 2011.
  • Optimizing magnetite nanoparticles for mass sensitivity in magnetic particle imaging. RM Ferguson, KR Minard, AP Khandhar, and KM Krishnan, Medical Physics, 38(3), 1619, 2011.
  • Ferrohydrodynamic Relaxometry for Magnetic Particle Imaging. PW Goodwill, A Tamrazian, LR Croft, CD Lu, EM Johnson, R Pidaparthi, RM Ferguson, AP Khandhar, KM Krishnan, and SM Conolly, Applied Physics Letters, 98, 262502, 2011.
  • Magnetic Particle Imaging process: One-Dimensional Signal, Bandwidth, SNR, and SAR. PW Goodwill, SM Conolly, IEEE Trans Med Img, 29(11), 2010.
  • Narrowband Magnetic Particle Imaging. PW Goodwill, G Scott, P Stang, SM Conolly, IEEE Trans Med Img, 28(8), 1231-7, 2009.
  • Three-dimensional real-time in vivo magnetic particle imaging. J Weizenecker, B Gleich, J Rahmer, H Dahnke, J Borgert, Phys Med Biol, 54(5):L1-L10, 2009.
  • Optimization of nanoparticle core size for magnetic particle imaging. RM Ferguson, KR Minard, and KM Krishnan, J. Magn Magn Mater, 321 (10), 1548–1551, 2009.
  • Signal encoding in magnetic particle imaging: properties of the system function. J Rahmer, J Weizenecker, B Gleich, and J Borgert, BMC Medical Imaging, 9(1), 2009.
  • Tomographic imaging using the nonlinear response of magnetic particles. B Gleich and J Weizenecker, Nature, 435 (7046), 1214–7, 2005.

Webinar Presentations

Webinar: The Basics of Magnetic Particle Imaging

Recorded Presentation Here

This presentation will introduce a ground-breaking, next generation imaging technology called magnetic particle imaging (MPI). We will review the basic theory behind MPI along with current and future application opportunities.

Webinar: Preclinical Applications in Magnetic Particle Imaging

Recorded Presentation Here

This presentation will introduce magnetic particle imaging (MPI) and current applications in preclinical imaging. MPI is the first molecular imaging technique simultaneously capable of: nanomolar sensitivity, absolute quantitation, resolution independent of depth, and with tracer detection from weeks to months. MPI is complementary to existing molecular imaging techniques, giving scientists a new versatile tool to accelerate cancer, infectious disease, cell tracking, and vascular research.

Webinar: Nanoparticle Development for Magnetic Particle Imaging Applications

Recorded Presentation Here

MPI is a revolutionary technique for imaging iron oxide tracers with high sensitivity and contrast. This presentation will be co-hosted by Magnetic Insight and LodeSpin Labs.

LodeSpin Labs is developing a suite of high-performance MPI-optimized nanoparticles. These unique nanoparticles start as iron oxide cores for maximum SNR and resolution. Added functional, biocompatible coatings extend blood circulation and support conjugation chemistry for a variety of applications. LS-008, LodeSpins Lab’s blood pool tracer, circulates for hours in mice, greatly enhancing the MPI imaging window and improving SNR and resolution compared with standard SPIO tracers.

Additionally, Magnetic Insight will discuss the versatility of available SPIO’s to support applications in cell tracking, functional targeting and interventional imaging.

Video Presentations

June 8, 2012. A big obstacle to developing stem cell therapies is being able to visualize the cells inside the body. This will be critical to confirm that the stem cells are targeted to the right place and are providing therapeutic benefit. Current imaging technology is not adequate for tracking stem cells in vivo.

March 23, 2013. The International Workshop on Magnetic Particle Imaging (IWMPI) is the premier forum for researchers working in the field of Magnetic Particle Imaging (MPI). The 3rd IWMPI took place at University of California, Berkeley on March 23-24, 2013. This video includes the opening remarks by Prof. Steven M. Conolly, the workshop chair.